US 8,540,664 B2 · Probablistic pharmacokinetic and pharmacodynamic modeling

Abstract

The subject matter disclosed herein provides a response to a dose of a substance and/or controls the administration of the dose. In one aspect, there is provided a system. The system may include a processor and at least one memory configured to provide a response determinator. The response determinator may receive therapeutic and wellness data. Moreover, the response determinator may determine a response based on the received therapeutic and wellness data. The response may represent a reaction to a substance integrated with an ingestible event marker. The determined response may be provided to, for example, a therapy controller. Related systems, methods, and articles of manufacture are also described.

Claims13

Dependent claims

A system comprising:

a processor;
and
at least one memory, the processor and the at least one memory configured to provide a response determinator to:
receive therapeutic and wellness data;
determine, based on the received therapeutic and wellness data, a response representing a reaction to a substance integrated with an ingestible event marker;
and provide the determined response;
and
wherein the response determinator determines the response as a response matrix, H, according to the following equation:
H=(ATA)−1ATY,
wherein A represents one or more times that a dose of the substance is ingested, AT represents a transpose of matrix A, (AT A)−1 represents an inverse of a matrix multiplication of matrix A and matrix AT, and Y represents a matrix of observations including the therapeutic and wellness data.

7 more elements

Dependencies are inferred from the claim text.

Facts

Application

13/260,073Filed 24 Mar 2010 · us provisional application

Priority

25 Mar 2009

Published

US 2012/0022443 A126 Jan 2012

Granted

24 Sep 2013

Term ends

Not estimatedThe source records don’t support an estimate.

Classification5 codes

G16H 20/13
Relating to drugs or medications, e.g. for ensuring correct administration to patients: delivered from dispensers
A61M 5/1723
Electrical or electronic: using feedback of body parameters, e.g. blood sugar or pressure
G16H 40/63
For the operation of medical equipment or devices: for local operation
G16H
Healthcare informatics, i.e. information and communication technology [ict] specially adapted for the

Probablistic pharmacokinetic and pharmacodynamic modeling

Life of this patent

Probablistic pharmacokinetic and pharmacodynamic modeling

Life of this patent

Abstract

Claims13