Bone-regeneration material
AssigneeDePuy Synthes Products, Inc.
InventorThierry Stoll
Life of this patent
Estimating the term…
Abstract
The invention relates to a process for producing a bone-regeneration material. According to the method, a bio-compatible, open-pored body is exposed to a vacuum and osteoinductive and/or osteogenic substances are absorbed into the pores of the body, for example by means of a vacuum generated therein. It is thus possible to produce a bone-regeneration material, which contains osteoinductive and/or osteogenic substances in the pores of the bio-compatible body, said substances acting as a network structure for new somatic cells that are to grow into the porous body.
Claims19
A process for the production of a bone regeneration material which contains a drawable substance that includes (i) at least one osteoinductive substance, (ii) at least one osteogenic substance, or (iii) at least one osteoinductive substance and at least one osteogenic substance, the process being performed with a syringe with a hollow cylinder, a piston, and an air tight seal and comprising:
- (a) housing a biocompatible, interconnected open-pore body in the hollow cylinder of the syringe;
- (b) forming a perforation in the air tight seal;
- (c) drawing the drawable substance through the perforation;
- (d) after drawing the drawable substance through the perforation, sealing the perforation;
- and
- (e) after sealing the perforation, drawing the drawable substance into pores of the biocompatible, interconnected open-pore body by further displacing the piston to create negative pressure within the hollow cylinder of the syringe.
A method, comprising:
- placing a biocompatible open-pore body in a chamber of a syringe;
- drawing at least one flowable substance into the chamber through a needle inserted through a membrane;
- removing the needle from the membrane to form an air tight seal;
- and
- after sealing the membrane, continuing to draw a syringe piston to produce a level of vacuum that is maintained within the chamber to draw the flowable substance into pores of the biocompatible open-pore body.
A method, comprising:
- placing a biocompatible resorbable open-pore body in a chamber of a hollow cylinder;
- coupling a membrane to said hollow cylinder to form an airtight seal;
- inserting a cannula through said membrane;
- drawing a flowable substance into the chamber through the cannula;
- removing the cannula from the membrane to reform the air tight seal;
- and
- after removing the cannula from the membrane to reform the air tight seal, producing and maintaining a level of vacuum within the chamber to draw the at least one flowable substance into pores of the biocompatible resorbable open-pore body and expel air from the biocompatible open-pre body as the flowable substance is drawn into the biocompatible resorbable open-pore body.
Dependencies are inferred from the claim text.