Extracorporeal pumping methods

An extracorporeal pumping method comprising:

• receiving an inlet fluid through a first tricuspid valve into a compressible-expandable bladder sealably mounted within a housing;
• moving an actuating member mounted within a fluid chamber of a hydraulic actuating sub-assembly, the fluid chamber containing a pressure transmissive fluid, and displacing transmissive fluid from the fluid chamber into the housing;
• compressing a volume of the bladder in the housing the transmissive fluid displaced into the housing, the compressed bladder ejecting the inlet fluid from the bladder through a second tricuspid valve to provide an outlet fluid under pulsatile pressure;
• moving the actuating member within the fluid chamber and returning the displaced transmissive fluid from the housing into the fluid chamber;
• expanding the compressed bladder in the housing and receiving additional inlet fluid into the bladder;
• programming a predetermined pulse rate, stroke volume, and upstroke rise time into a motion controller, the motion controller controlling pulse rate, stroke volume, and upstroke rise time independently;
• controlling the movement of the actuating member using the motion controller such that the outlet fluid exhibits the predetermined pulse rate, stroke volume, and upstroke rise time;
• monitoring the position and velocity of a shaft in a communicating motor system, the shaft acting on the actuating member to generate the movement of the actuating member;
• and
• using the outlet fluid under the pulsatile pressure to extract umbilical cord blood and/or placenta stem cells or to provide stem cell therapy, cardiopulmonary bypass, ventricular assist, extracorporeal membrane oxygenation, organ preservation, fetal cardiac bypass, or cancer treatment.