Back to results
US 8,465,971 B2Granted
Method for controlling biological function with mechanical vibration and device therefor
AssigneeTokyo Iken Co., Ltd.
InventorsAkio Kishida, Tsutomu Furuzono, Kozo Miyazaki, Toru Masuzawa
Life of this patent
Estimating the term…
Abstract
Methods and apparatus for controlling biological functions with mechanical vibration are provided. Stimulation is applied to cells of one of an organism, bacteria or virus by mechanical vibration. The biological function comprises biological functions relating to cell growth. The biological functions relating to cell growth may include at least one of cell cultivation, cell proliferation, cell fusion, and cell differentiation.
Claims6
Apparatus for controlling biological functions with mechanical vibration, comprising:
- an airtight chamber;
- means for generating mechanical vibration arranged in the airtight chamber, said means for generating mechanical vibration comprising:
- a piezoelectric element for generating mechanical vibration in a horizontal direction;
- and
- at least one of:
- (a) a plurality of vibration elements for generating mechanical vibration in a longitudinal direction;
- and (b) an array of transducers for generating mechanical vibration in the longitudinal direction;
- a solid substrate arranged on the means for generating mechanical vibration and in contact with cells of one of an organism, bacteria or virus, said solid substrate adapted to transfer said mechanical vibration directly to said cells for stimulating said cells;
- a temperature adjusting device for controlling temperature in the airtight chamber;
- means for controlling the means for generating mechanical vibration to generate the mechanical vibration at an amplitude and a frequency conducive to stimulating biological functions relating to cell growth;
- means for real-time monitoring and recording of said cell growth produced by the mechanical vibration;
- wherein said biological functions relating to cell growth comprise at least one of cell cultivation, cell proliferation, cell fusion, and cell differentiation.
9 more elements
Dependencies are inferred from the claim text.