Method for detection of disease having insulin-resistant conditions
AssigneeJapan Science and Technology Agency
InventorJinichi Inokuchi
Life of this patent
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Abstract
Disclosed is a simple method for detecting a pathological condition of an insulin-resistant disease, particularly type-2 diabetes. The method comprises quantifying the ganglioside GM3 in a blood sample separated from a living body. More specifically, the method comprises the following steps (a) to (c): (a) separating a plasma or serum from the blood collected from a human; (b) quantifying the ganglioside GM3 in the plasma or serum; and (c) comparing the quantified ganglioside GM3 level to the mean ganglioside GM3 level determined in blood samples from healthy volunteers.
Claims11
A method for detection of a disease selected from the group consisting of type 2 diabetes and type 2 diabetes combined with hyperlipidemia, wherein said type 2 diabetes group having a Body Mass Index level greater than 30, which comprises:
- separating plasma or serum from human blood collected;
- quantifying ganglioside GM3 in the plasma or serum separated;
- and,
- comparing the GM3 level quantified to a mean ganglioside GM3 level in blood samples derived from healthy volunteers, thereby detecting the disease.
A method for predicting a risk of developing a disease selected from the group consisting of type 2 diabetes and type 2 diabetes combined with hyperlipidemia, wherein said type 2 diabetes group having a Body Mass Index level greater than 30, which comprises:
- separating plasma or serum from human blood collected;
- quantifying ganglioside GM3 in the plasma or serum separated;
- comparing the GM3 level quantified to a normal ganglioside GM3 level in blood samples from healthy volunteers;
- and
- monitoring changes in the ganglioside GM3 level, thereby predicting the risk.
Dependencies are inferred from the claim text.