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US 8,465,736 B2Granted
Glutadon
AssigneeNew Medical Enzymes AG
InventorsMichael Bausch, Wetzler Rainer, Christian Muller
Life of this patent
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Abstract
The present invention relates to a pharmaceutical combination product for cancer therapy. The combination product comprises the two active ingredients glutaminase and 6-diazo-5-oxo-L-norleucine (DON). The invention further relates to the use of such a combination product for the treatment of cancers.
Claims10
A combination product for cancer treatment, which combination product comprises the active ingredients
- a) glutaminase and
- b) 6-diazo-5-oxo-L-norleucine (DON),
- where active ingredient a) is present in a dosage of from 40 I.U./m2 to 300 I.U./m2 based on a recipient;
- and
- where active ingredient b) is present in a dosage of from 105 to 185 mg/m2 based on a recipient, where in the glutaminase is a glutaminase asparaginase from Pseudomonas 7A.
2 more elements
Dependencies are inferred from the claim text.