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US 8,367,701 B2Granted
Crystalline pharmaceutical and methods of preparation and use thereof
AssigneeSarcode Bioscience Inc.
InventorsJohn Burnier, Thomas Gadek, Frederic Naud
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Abstract
Novel crystalline polymorphic forms, Forms A, B, C, D, and E of a compound of Formula I, which has been found to be a potent inhibitor of LFA-1, are disclosed. Methods of preparation and uses thereof in the treatment of LFA-1 mediated diseases are also disclosed in this invention.
Claims41
A composition comprising a compound of Formula I:
- comprising a purity of greater than about 90%, and/or a pharmaceutically acceptable salt thereof.
A compound of the formula:
- or its pharmaceutically acceptable salts.
Dependencies are inferred from the claim text.