Heteroaryl compounds as P2Y1 receptor inhibitors

A compound of Formula (II):

• or a stereoisomer, a tautomer, or a pharmaceutically acceptable salt thereof, wherein:
• ring A is
• R1c is independently C1-6 alkyl substituted with 0-2 Ra, C2-6 alkenyl substituted with 0-2 Ra, C2-6 alkynyl substituted with 0-2 Ra, Br, CN, CF3, —CF2CF3, —C(NH2)═N(OH), C(O)Rc, —CH(═NOH), —C(O)ORc, NR12R13, —C(O)NR12R13, —CON(Me)(CH2)2OH, —S(O)pNR12R13, —(CH2)r—C3-6 cycloalkyl substituted with 0-2 Rb, —(CH2)r-adamantyl substituted with 0-2 Rb, —(CH2)r-phenyl substituted with 0-4 Rb, or —(CH2)r-naphthyl substituted with 0-4 Rb;
• R5 is phenyl substituted with 1-4 R5a;
• R5a is, independently at each occurrence, F, Cl, Br, I, —(CRiRi)r—ORc, SRc, CN, CF3, —CF2CF3, OCF3, —OCF2CF2H, —OCF2CF3, —NR12R13, —C(O)Rc, —C(O)ORc, —C(O)NR12R13, —NR14C(O)Rd, —S(O)pNR12R13, —S(O)Rd, —S(O)2Rd, —Si(Me)3, Si(C1-4 alkyl)3, C1-4 haloalkyl, C1-4 haloalkyloxy-, C1-4 alkyloxy-, C1-4 alkylthio-, C1-4 alkyl-C(O)—, C1-4 alkyl-O—C(O)—, C1-4 alkyl-C(O)NH—, C1-8 alkyl substituted with 0-2 Ra, C2-8 alkenyl substituted with 0-2 Ra, C2-8 alkynyl substituted with 0-2 Ra, or —(CRfRf)r—C3-10 carbocycle substituted with 0-3 Re;
• alternatively, two R5a groups attached to two adjacent carbon atoms, together with the carbon atoms to which they are attached, form a 5- to 7-membered carbocyclic ring, wherein said carbocyclic ring is substituted with 0-3 Re;
• R7 is H, Br, CN, NH2, NMe2, or —NH(4-OMe-Ph);
• R8 is H, Br, CN, NMe2, or —N(Me)(4-OMe-Ph);
• R11 is, independently at each occurrence, H, —COPh, —COBn, —SO2Me, —SO2Ph, —SO2Bn, C1-6 alkyl substituted with 1-5 fluorine, —(CRfRf)rC(O)NR12R13, C1-4 alkyl substituted with 0-2 Ra, —(CH2)r—C3-6 cycloalkyl substituted with 0-2 Rb, —(CH2)r-phenyl substituted with 0-3 Rb, or —CHMe-phenyl substituted with 0-3 Rb;
• R12 is, independently at each occurrence, H, C1-6 alkyl substituted with 1-5 fluorine, —(CRfRf)rC(O)NRfRf, C1-6 alkyl, —(CH2)r—C3-6 cycloalkyl, or —(CH2)n-phenyl;
• wherein said alkyl and phenyl are substituted with 0-2 Rg;
• R13 is, independently at each occurrence, H, C1-6 alkyl, or —(CH2)n-phenyl;
• R14 is, independently at each occurrence, H, C1-6 alkyl, C2-6 alkenyl, or —(CH2)r-phenyl carbocycle substituted with 0-3 Rg;
• Ra is, independently at each occurrence, H, F, OCF3, CF3, —(CRfRf)rORc, —(CRfRf)rSRc, CN, —(CRfRf)rNR12R13, —(CRfRf)rC(O)Rc, —(CRfRf)rC(O)ORc, —(CRfRf)rC(O)NR12R13, —(CRfRf)rNR14C(O)Rd, —(CRfRf)rS(O)pNR12R13, —(CRfRf)rS(O)Rd, —(CRfRf)rS(O)2Rd, C1-4 alkyl substituted with 1-5 fluorine, or —(CH2)r—C3-10 carbocycle substituted with 0-3 Re;
• Rb is, independently at each occurrence, C1-6 alkyl substituted with 0-2 Ra, C2-6 alkenyl substituted with 0-2 Ra, C2-6 alkynyl substituted with 0-2 Ra, F, Cl, Br, CF3, —OCF3, —(CH2)r—ORc, —(CH2)r—C(O)ORc, —(CRfRf)rNR12R13, —(CH2)r—C(O)NR12R13, CN, —OCH2C(Me)2CH2NMe2, NO2, —SO2Me, OBn, —(CH2)r—C3-6 cycloalkyl, —(CH2)r-phenyl substituted with 0-2 Re, or —(CH2)r-naphthyl substituted with 0-3 Re;
• Rd is, independently at each occurrence, CF3, OH, C1-4 alkoxy, C1-6 alkyl, or —(CH2)r—C3-10 carbocycle substituted with 0-2 Re;
• Re is, independently at each occurrence, H, ═O, —(CH2)r—ORf, F, Cl, Br, I, CN, NO2, —(CH2)r—NR12R13, —C(O)Rf, —(CH2)r—C(O)ORf, —NR14C(O)Rf, —(CH2)r—C(O)NR12R13, —SO2NR12R13, —NR14SO2NR12R13, —NR14SO2—C1-4 alkyl, —NR14SO2CF3, —NR14SO2-phenyl, —S(O)2CF3, —S(O)p—C1-4 alkyl, —S(O)p-phenyl, —(CF2)rCF3, Si(C1-4 alkyl)3, C1-8 alkyl substituted with 0-2 Rg, C2-8 alkenyl substituted with 0-2 Rg, C2-8 alkynyl substituted with 0-2 Rg, —(CH2)r—C3-8 cycloalkyl substituted with 0-2 Rg, or —(CH2)r—C6-10 aryl substituted with 0-2 Rg;
• alternatively, two Re groups, together with the atoms to which they are attached, form a 5- to 7-membered carbocyclic ring, wherein said carbocyclic ring is substituted with 0-2 Rg;
• Rf is, independently at each occurrence, H, F, C1-6 alkyl, or —(CH2)n-phenyl;
• Rg is, independently at each occurrence, H, ═O, ORf, F, Cl, Br, I, CN, NO2, —NRfRf, —C(O)Rf, —C(O)ORf, —NRfC(O)Rf, —C(O)NRfRf, —SO2NRfRf, —NRfSO2NRfRf, —NRfSO2—C1-4 alkyl, —NRfSO2CF3, —NRfSO2-phenyl, —S(O)2CF3, —S(O)p—C1-4 alkyl, —S(O )p-phenyl, —(CF2)rCF3, C1-6 alkyl, C2-6 alkenyl, or C2-6 alkynyl;
• Ri is, independently at each occurrence, H or C1-6 alkyl;
• n, at each occurrence, is selected from 0, 1, 2, 3, and 4;
• p, at each occurrence, is selected from 0, 1, and 2;
• and
• r, at each occurrence, is selected from 0, 1, 2, 3, and 4.