Vaccine against african horse sickness virus
AssigneesMerial Limited, The Regents of the University of California, University of Pretoria
InventorsJules Maarten Minke, Jean-Christophe Audonnet, Alan John Guthrie, Nigel James MacLachlan, Jiansheng Yao
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Abstract
The present invention provides vectors that contain and express in vivo the genes encoding VP2 and VP5 of African Horse Sickness Virus or an epitope thereof that elicits an immune response in a horse against African horse sickness virus, compositions comprising said vectors, methods of vaccination against African horse sickness virus, and kits for use with such methods and compositions.
Claims15
An immunogenic composition comprising
- a recombinant poxvirus wherein the recombinant poxvirus comprises two nucleic acid molecules encoding polypeptides African Horse Sickness Virus (AHSV) VP2 and AHSV VP5;
- and wherein the composition is capable of eliciting a protective immune response in an equine animal.
An expression vector comprising one or more polynucleotide selected from the sequence as set forth in SEQ ID NO:4, the sequence as set forth in SEQ ID NO:5, and the combination of both.
Dependencies are inferred from the claim text.