Ophthalmic and otorhinolaryngological device materials containing a multi-arm PEG macromer

A polymeric ophthalmic or otorhinolaryngological device material comprising

• a) 75 to 97% (w/w) of a monofunctional acrylate or methacrylate monomer of formula [1]:
• wherein
• B═O(CH2)n, NH(CH2), or NCH3(CH2)n;
• R1═H, CH3, CH2CH3, or CH2OH;
• n=0-12;
• A=C6H5 or O(CH2)mC6H5, where the C6H5 group is optionally substituted with —(CH2)nH, —O(CH2)nH, —CH(CH3)2, —C6H5, —OC6H5, —CH2C6H5, F, Cl, Br, or I;
• and
• m=0-22;
• b) a difunctional acrylate or methacrylate cross-linking monomer of formula [2]:
• wherein
• R2, R3 independently=H, CH3, CH2CH3, or CH2OH;
• W, W′ independently=O(CH2)d, NH(CH2)d, NCH3(CH2)d, O(CH2)dC6H4, O(CH2CH2O)dCH2, O(CH2CH2CH2O)dCH2, O(CH2CH2CH2CH2O)dCH2, or nothing;
• J=(CH2)a, O(CH2CH2O)b, O, or nothing, provided that if W and W′=nothing, then J≠nothing;
• d=0-12;
• a=1-12;
• and
• b=1-24;
• and
• c) 1 to 8% (w/w) of a macromer of formula [3]:
• wherein
• k=2-75;
• s=0 or 1;
• t=0-4;
• Y independently=H, C(O)CCH2R4, CH2CH2NH2, CH2CH2NHC(O)CCH2R4, CH2CH2CH(OH)CH2OC(O)CCH2R4, CH2CH2NHC(O)NHCH2CH2OC(O)CCH2R4, C(O)NHCH2CH2OC(O)CCH2R4, or CH2CH2SH;
• and
• R4=H, CH3, CH2CH3, or CH2OH;
• and wherein the polymeric device material has an equilibrium water content (EWC) of 0.5 to 3%.