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US 8,148,146 B2Granted
Cell line
AssigneeUniversity of Pittsburgh—Of the Commonwealth System of Higher Education
InventorsJoseph C. Glorioso, Darren Wolfe, David Krisky
Life of this patent
Estimating the term…
Abstract
The invention provides a cell line complementing HSV ICP4, ICP27, and UL55 genes.
Claims3
A cell line that contains herpes simplex virus (HSV) ICP4, ICP27, and UL55 genes, wherein the cell line supports the replication of an HSV vector comprising deletions in ICP4, ICP27, and UL55 genes, wherein the vector does not comprise a deletion in UL56.
Dependencies are inferred from the claim text.