Interferon-like proteins and uses thereof
AssigneeAmgen Inc.
InventorsAndrew Welcher, Duanzhi Wen, Michael Kelley
Life of this patent
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Abstract
The present invention provides Interferon-Like (IFN-L) polypeptides and nucleic acid molecules encoding the same. The invention also provides selective binding agents, vectors, host cells, and methods for producing IFN-L polypeptides. The invention further provides pharmaceutical compositions and methods for the diagnosis, treatment, amelioration, and/or prevention of diseases, disorders, and conditions associated with IFN-L polypeptides.
Claims13
An isolated polypeptide comprising an amino acid sequence:
- (a) as set forth in SEQ ID NO:
- 5;
- or
- (b) encoded by the DNA insert in ATCC Deposit No. PTA-976.
An isolated polypeptide comprising the amino acid sequence as set forth in SEQ ID NO:
- 6, optionally further comprising an amino-terminal methionine.
An isolated polypeptide encoded by a nucleic acid molecule comprising a nucleotide sequence:
- (a) as set forth in SEQ ID NO:
- 4;
- (b) of the DNA insert in ATCC Deposit No. PTA-976;
- or
- (c) encoding a polypeptide as set forth in SEQ ID NO:
- 5.
A polypeptide produced by a process comprising culturing a host cell comprising a vector comprising a nucleic acid molecule comprising a nucleotide sequence:
- (a) as set forth in SEQ ID NO:
- 4;
- (b) of the DNA insert in ATCC Deposit No. PTA-976;
- or
- (c) encoding a polypeptide as set forth in SEQ ID NO:
- 5;
- under suitable conditions to express the polypeptide, and optionally isolating the polypeptide from the culture.
Dependencies are inferred from the claim text.