Detection of chronic kidney disease patients or coronary artery disease using bone morphogenic protein-4
AssigneeOchsner Clinic Foundation
InventorsThomas Cooper Woods, Corey Keith Goldman
Life of this patent
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Abstract
The invention is a method of detecting CAD in a CKD diagnosed human patient or CKD in a CAD diagnosed human patient, or detection of the presence of both CKD and CAD by assaying a plasma or serum sample of a human patient for elevated levels of BMP-4.
Claims8
A method comprising the steps of assaying a serum or plasma sample of a human patient for BMP-4 levels and diagnosing the presence of CAD when said BMP-4 levels are above 100 pg/mL.
A method comprising the steps of assaying a serum or plasma sample of a human patient for BMP-4 levels and diagnosing the presence of CAD and CKD when said BMP-4 levels are greater than 105 pg/mL.
A method comprising the steps of assaying a serum or plasma sample of a human patient for BMP-4 levels and diagnosing the absence of CAD when said BMP-4 levels are less than 100 pg/mL.
A method comprising the steps of assaying a serum or plasma sample of a human patient for BMP-4 levels and diagnosing the absence of CAD and CKD when said BMP-4 levels are less than 100 pg/mL, said method further including the step of assaying said serum or plasma sample of said human patient for creatinine levels and confirming the absence of CAD and CKD when said creatinine levels are less than 1.4 mg/dL for a male patient or less than 1.2 mg/dL for a female patient.
Dependencies are inferred from the claim text.