Phenylthiocarbamide (PTC) taste receptor
AssigneesThe United States of America, as represented by the Secretary, Department of Health and Human Services, University of Utah Research Foundation
InventorsDennis Drayna, Un-Kyung Kim, Mark Leppert
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Abstract
The invention provides isolated nucleic and amino acid sequences of a taste cell receptor that serves as a sensor for the bitter taste of phenylthiocarbamide (PTC), antibodies to such PTC taste receptor, methods of detecting such nucleic and amino acid sequences, and methods of screening for modulators of such PTC taste receptor.
Claims14
An isolated nucleic acid molecule that encodes a PTC taste receptor, or non-transmembrane fragment thereof, comprising at least 14 nucleotides of SEQ ID NO:
- 1 or SEQ ID NO:
- 3, wherein the nucleic acid molecule comprises nucleotide 145 of SEQ ID NO:
- 1 or SEQ ID NO:
- 3.
Dependencies are inferred from the claim text.