pRNA chimera
AssigneePurdue Research Foundation
InventorsPeixuan Guo, Stephen M. Hoeprich, Dan Shu
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Abstract
A polyvalent multimeric complex formed from a plurality of circularly permuted chimeric pRNA molecules, each carrying a stabilized biologically active moiety.
Claims19
A polyvalent multimeric complex comprising a plurality of chimeric pRNA monomers, each said chimeric pRNA monomer independently comprising a heterologous component that comprises a biologically active RNA.
A chimeric pRNA monomer comprising 5′ and 3′ ends, wherein at least one of said 5′ and 3′ ends comprises a heterologous component that comprises a biologically active RNA, and wherein the chimeric pRNA monomer is capable of assembling into a polyvalent multimeric complex comprising a plurality of chimeric pRNA monomers.
Dependencies are inferred from the claim text.