Composition comprising a purified collagen-like polypeptide suitable as a peptizer

A composition comprising a purified collagen-like polypeptide suitable as a peptizer, said polypeptide comprising [Gly-X-Y] repeats, wherein Gly stands for glycine, X and Y represent any amino acid and selected such that the length of the [Gly-X-Y] repeat being such that its weight on amino acid basis is at least 2.5 kDa and wherein the amino acid sequence of said polypeptide comprises more than 4 different amino acids and wherein said purified polypeptide is free of helix structure, and wherein said polypeptide is free of all the sequences LXXR (SEQ ID NO:51), IXXR (SEQ ID NO:52), VXXR (SEQ ID NO:53), MXXR (SEQ ID NO:54), and MGPR (SEQ ID NO. 14), and said polypeptide having a molecular weight on amino acid basis of at least 10 kDa, said polypeptide comprising less than 100 ppm nucleic acids.

A composition comprising a purified collagen-like polypeptide suitable as a peptizer, said polypeptide comprising [Gly-X-Y] repeats, wherein Gly stands for glycine, X and Y represent any amino acid and selected such that the length of the [Gly-X-Y] repeat being such that its weight on amino acid basis is at least 2.5 kDa and wherein the amino acid sequence of said polypeptide comprises more than 4 different amino acids and wherein said purified polypeptide is free of helix structure, wherein the amino acid sequence of said polypeptide has more than 50% homology to native collagen type I, II or III, and wherein said polypeptide is free of all the sequences LXXR (SEQ ID NO:51), IXXR (SEQ ID NO:52), VXXR (SEQ ID NO:53), MXXR (SEQ ID NO:54), and MGPR (SEQ ID NO. 14).

A composition comprising a purified collagen-like polypeptide suitable as a peptizer, said polypeptide comprising [Gly-X-Y] repeats, wherein Gly stands for glycine, X and Y represent any amino acid and selected such that the length of the [Gly-X-Y] repeat being such that its weight on amino acid basis is at least 2.5 kDa and wherein the amino acid sequence of said polypeptide comprises more than 4 different amino acids and wherein said purified polypeptide is free of helix structure, wherein the amino acid sequence of said polypeptide is at least 80% identical to a native collagen type I, II or III, and wherein said polypeptide is free of all the sequences LXXR (SEQ ID NO:51), IXXR (SEQ ID NO:52), VXXR (SEQ ID NO:53), MXXR (SEQ ID NO:54), and MGPR (SEQ ID NO. 14).

A composition comprising a purified collagen-like polypeptide suitable as a peptizer, said polypeptide comprising [Gly-X-Y] repeats, wherein Gly stands for glycine, X and Y represent any amino acid and selected such that the length of the [Gly-X-Y] repeat being such that its weight on amino acid basis is at least 2.5 kDa and wherein the amino acid sequence of said polypeptide comprises more than 4 different amino acids and wherein said purified polypeptide is free of helix structure, wherein the amino acid sequence of said polypeptide is substantially the same as occurs in nature for collagen type I, and wherein polypeptide is free of all the sequences LXXR (SEQ ID NO:51), IXXR (SEQ ID NO:52), VXXR (SEQ ID NO:53), MXXR (SEQ ID NO:54) and MGPR (SEQ ID NO:

• 14).

A composition comprising a purified collagen-like polypeptide suitable as a peptizer, said polypeptide comprising [Gly-X-Y] repeats, wherein Gly stands for glycine, X and Y represent any amino acid and selected such that the length of the [Gly-X-Y] repeat being such that its weight on amino acid basis is at least 2.5 kDa and wherein the amino acid sequence of said polypeptide comprises more than 4 different amino acids and wherein said purified polypeptide is free of helix structure, and wherein said polypeptide is free of all the sequences LXXR (SEQ ID NO:51), IXXR (SEQ ID NO:52), VXXR (SEQ ID NO:53), MXXR (SEQ ID NO:54), and MGPR (SEQ ID NO. 14), and said polypeptide having a molecular weight on amino acid basis of at least 10 kDa, wherein said polypeptide has an iso-electric point of 7-10.

A composition comprising a purified collagen-like polypeptide suitable as a peptizer, said polypeptide comprising [Gly-X-Y] repeats, wherein Gly stands for glycine, X and Y represent any amino acid and selected such that the length of the [Gly-X-Y] repeat being such that its weight on amino acid basis is at least 2.5 kDa and wherein the amino acid sequence of said polypeptide comprises more than 4 different amino acids and wherein said purified polypeptide is free of helix structure, and wherein said polypeptide is free of all the sequences LXXR (SEQ ID NO:51), IXXR (SEQ ID NO:52), VXXR (SEQ ID NO:53), MXXR (SEQ ID NO:54) and MGPR (SEQ ID NO:14), wherein said polypeptide has a molecular weight on an amino acid basis of 2.5-100 kDa.

A composition comprising a purified collagen-like polypeptide suitable as a peptizer, said polypeptide comprising [Gly-X-Y] repeats, wherein Gly stands for glycine, X and Y represent any amino acid and selected such that the length of the [Gly-X-Y] repeat being such that its weight on amino acid basis is at least 2.5 kDa and wherein the amino acid sequence of said polypeptide comprises more than 4 different amino acids and wherein said purified polypeptide is free of helix structure, and wherein said polypeptide is free of all the sequences LXXR (SEQ ID NO:51), IXXR (SEQ ID NO:52), VXXR (SEQ ID NO:53), MXXR (SEQ ID NO:54), and MGPR (SEQ ID NO. 14), and said polypeptide having a weight on an amino acid basis of at least 10 kDa, wherein said polypeptide is free of cysteine.

A composition comprising a purified collagen-like polypeptide suitable as a peptizer, said polypeptide comprising [Gly-X-Y] repeats, wherein Gly stands for glycine, X and Y represent any amino acid and selected such that the length of the [Gly-X-Y] repeat being such that its weight on amino acid basis is at least 2.5 kDa and wherein the amino acid sequence of said polypeptide comprises more than 4 different amino acids and wherein said purified polypeptide is free of helix structure, and wherein said polypeptide is free of all the sequences LXXR (SEQ ID NO:51), IXXR (SEQ ID NO:52), VXXR (SEQ ID NO:53), MXXR (SEQ ID NO:54), and MGPR (SEQ ID NO. 14), and said polypeptide having a weight on amino acid basis of at least 10 kDa, wherein said polypeptide is stable during silver halide tabular grain formation at a pH between 4-8.