Compositions and methods for treatment of microbial infections
AssigneeImmunology Laboratories, Inc.
InventorsJiri Pillich, John C. Balcarek
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Abstract
The present invention relates to methods and compositions for treatment of microbial infections and for the enhancement of resistance to infection. The invention comprises administration of an effective amount of a protein isolated from bacterial lysate compositions for the treatment of pathological conditions of microbial infections. The present invention can also be used to enhance the immune system to prevent infections by the administration of an effective amount of the compositions.
Claims9
A method of treating pathological conditions resulting from a Staphylococcus aureus (S. aureus) infection in humans or animals, comprising, administering to a human or animal having said pathological condition, a composition comprising at least one phage capsid protein isolated from a bacterial lysate derived from the infection of at least one bacterial strain of S. aureus, deposited with the Czech Collection of Microorganisms (CCM) under accession number CCM 4992 with at least one bacteriophage deposited with the Deutsche Sammlung von Mikroorganismen and Zellkulturen GmBH (DSM) having accession number DSM 14614, DSM 14615, or DSM 14616 and wherein the phage capsid protein has a molecular weight of 50 kDa.
A method of preventing a Staphylococcus aureus (S. aureus) infection or pathological conditions resulting from said S. aureus infection comprising administering to a human or animal a composition comprising at least one phage capsid protein isolated from a bacterial lysate derived from the infection of at least one bacterial strain of S. aureus deposited with the Czech Collection of Microorganisms (CCM) under accession number CCM 4992 with a bacteriophage deposited with the Deutsche Sammlung von Mikroorganismen and Zellkulturen GmBH (DSM) having accession number DSM 14614, DSM 14615, or DSM 14616 and wherein the phage capsid protein has a molecular weight of 50 kDa.
Dependencies are inferred from the claim text.