Interfacing a prefilled syringe with an infusion pump to fill the infusion pump

A method of filling an infusion pump with therapeutic liquid using a prefilled syringe, the method comprising:

• obtaining a prefilled syringe, the prefilled syringe comprising a prefilled vial containing a predetermined quantity of therapeutic liquid, the prefilled vial having a dispensing end;
• obtaining an infusion pump comprising a pump housing and a reservoir within the housing, the housing comprising a base including a syringe coupling region, the syringe coupling region including a fill port and a recessed portion recessed into the pump housing, wherein a needle is located in the recessed portion of the syringe coupling region, the needle having a first end passing through the fill port and a second end being recessed beneath an outer surface of the base;
• coupling the dispensing end of the prefilled vial to the syringe coupling region of the infusion pump by threadably engaging the recessed portion of the syringe coupling region with the dispensing end such that the needle passes through the dispensing end as the dispensing end is engaged and such that the prefilled vial is fluidly coupled to the reservoir via the fill port;
• dispensing a predetermined amount of therapeutic liquid from the prefilled vial into the reservoir;
• and
• removing the dispensing end of the prefilled vial from the syringe coupling region.