Lipid nanotube or nanowire sensor
AssigneeLawrence Livermore National Security, LLC
InventorsAleksandr Noy, Olgica Bakajin, Sonia Létant, Michael Stadermann, Alexander B. Artyukhin
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Abstract
A sensor apparatus comprising a nanotube or nanowire, a lipid bilayer around the nanotube or nanowire, and a sensing element connected to the lipid bilayer. Also a biosensor apparatus comprising a gate electrode; a source electrode; a drain electrode; a nanotube or nanowire operatively connected to the gate electrode, the source electrode, and the drain electrode; a lipid bilayer around the nanotube or nanowire, and a sensing element connected to the lipid bilayer.
Claims21
A nanoscale sensor apparatus for detection of biological toxins, comprising:
- a base,
- a microfluidic channel in said base,
- a gate in said microfluidic channel,
- a source in said microfluidic channel,
- a drain in said microfluidic channel,
- a lipid bilayer-carbon nanotube or nanowire transistor in said microfluidic channel, said lipid bilayer-carbon nanotube or nanowire transistor connected to said gate, said source, and said drain, said lipid bilayer-carbon nanotube or nanowire transistor including
- a nanotube or nanowire,
- a lipid bilayer around said nanotube or nanowire,
- a hydrophilic cushion between said nanotube or nanowire and said lipid bilayer, wherein said hydrophilic cushion is a polymer cushion,
- a sensing element connected to said lipid bilayer, and
- a cover covering said microfluidic channel.
A nanoscale biosensor apparatus for detection of biological toxins, comprising:
- a base,
- a microfluidic channel in said base,
- a gate electrode in said microfluidic channel;
- a source electrode in said microfluidic channel;
- a drain electrode in said microfluidic channel;
- a lipid bilayer-carbon nanotube or nanowire transistor in said microfluidic channel, said lipid bilayer-carbon nanotube or nanowire transistor including
- a nanotube or nanowire operatively connected to said gate electrode, said source electrode, and said drain electrode;
- a lipid bilayer around said nanotube or nanowire,
- a hydrophilic cushion between said nanotube or nanowire and said lipid bilayer,
- a sensing element connected to said lipid bilayer, and
- a cover covering said microfluidic channel.
Dependencies are inferred from the claim text.