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US 7,745,693 B2Granted
Inhibitors of plant peptide deformylase for use as broad-spectrum herbicides and methods for identifying the same
AssigneeUniversity of Kentucky Research Foundation
InventorsRobert L. Houtz, Lynnette M. A. Dirk, Mark Alan Williams
Life of this patent
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Abstract
The invention relates to a method of identifying herbicides and to the use of inhibitors of plant peptide deformylase as broad spectrum herbicides.
Claims6
A method of preparing an herbicide-resistant plant, comprising:
- a) transforming recipient plant cells with a nucleic acid molecule encoding a plant peptide deformylase having peptide deformylase activity;
- b) selecting a recipient plant cell comprising the nucleic acid molecule, c) contacting the selected recipient plant cell of (b) with an herbicide that inhibits plant peptide deformylase activity;
- d) selecting a recipient plant cell of (c) that is resistant to the herbicide;
- and e) regenerating a plant from the selected recipient plant cell, wherein the plant comprises enhanced herbicide resistance relative to a corresponding non-transformed plant and wherein the plant peptide deformylase comprises the amino acid sequence of SEQ ID NO:
- 8.
2 more elements
A method of selectively growing herbicide-resistant plants, the method comprising the steps of:
- a) growing plants comprising elevated levels of plant peptide deformylase relative to a corresponding wild type plant;
- and b) contacting the plants with an amount of an herbicide comprising an inhibitor of plant peptide deformylase sufficient to prevent growth of a corresponding plant which does not over-express plant peptide deformylase wherein the plant peptide deformylase is encoded by a transgene and wherein the plant peptide deformylase comprises the amino acid sequence of SEQ ID NO:
- 8.
Dependencies are inferred from the claim text.