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US 7,745,613 B2Granted
Method for preparing peritoneal dialysate
AssigneesToshio Miyata, Kiyoshi Kurokawa, Tokai University Educational System
InventorToshio Miyata
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AssigneesToshio Miyata, Kiyoshi Kurokawa, Tokai University Educational System
InventorToshio Miyata
Estimating the term…
Carbonyl compounds generated and accumulated in the peritoneal dialysate can be inactivated or eliminated by a carbonyl compound-trapping agent such as aminoguanidine. Carbonyl compounds generated during sterilization and storage of the peritoneal dialysate can be eliminated by pre-contacting with the trapping agent. Further, it is possible to eliminate carbonyl compounds transferred from the blood to the peritoneal cavity of the patient during peritoneal dialysis treatment, by adding the trapping agent to the peritoneal dialysate or by circulating the fluid through a carbonyl compound-trapping cartridge. Intraperitoneal protein modification by carbonyl compounds is inhibited by the present invention, thereby sufficiently reducing peritoneal disorders associated with peritoneal dialysis treatment.
An agent for improving intraperitoneal carbonyl-stress state during peritoneal dialysis, comprising pyridoxines or salts thereof as an active ingredient wherein the pyridoxines or salts thereof are immobilized on an insoluble carrier.
A cartridge, comprising:
A method for preparing a peritoneal dialysate, comprising:
A method for preparing a peritoneal dialysate having a reduced carbonyl compound content, the method comprising:
A peritoneal dialysate present in a dual compartment container wherein a first compartment contains a reducing sugar and a second compartment contains pyridoxines or salts thereof.
Dependencies are inferred from the claim text.