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AssigneePrometic Biosciences Inc.
InventorsLyne Gagnon, Jean Barabe, Pierre Laurin, Christopher Penney, Boulos Zacharie
Estimating the term…
A composition and method for promoting neutrophil survival and activation such as the treatment of neutropenia arising as an undesirable side effect of chemotherapy and radiation therapy. A composition containing medium-chain fatty acids, such as Capri acid or caprylic acid, or salts or triglycerides thereof, or mono- or diglycerides or other analogues thereof or medium-chain triglycerides (MCT) is administered to a human or animal needing treatment in an amount sufficient to reduce or eliminate neutropenia. The composition is administered in an amount effective to treat the disorder. The methods are also useful in the management of bone narrow transplantation and in the treatment of various neutropenic diseases.
A method of stimulating hematopoiesis in a patient in need of such stimulation, wherein said stimulation of hematopoiesis is used to treat myelosuppression arising from chemotherapy or radiotherapy in the patient, said method comprising administering to said patient a pharmacologically effective amount of a composition comprising a purified caprylic salt or caprate salt, wherein said administration is done by a route selected from oral, sublingual, pulmonary, intramuscular, intradermal, subcutaneous and intravenous;
A method of stimulating hematopoiesis in a patient in need of such stimulation, wherein said stimulation of hematopoiesis induces neutrophil mobilization to facilitate bone marrow transplantation in said patient, said method comprising administering to said patient a pharmacologically effective amount of a purified caprylic salt or caprate salt, wherein said administration is done by a route selected from oral, sublingual, pulmonary, intramuscular, intradermal, subcutaneous and intravenous;
Dependencies are inferred from the claim text.