Non-irritating compositions containing zinc salts
AssigneeThe Trustees of Columbia University in the City of New York
InventorsShanta M. Modak, Milind S. Shintre, Lauserpina Caraos, Trupti Gaonkar, Ingrid Geraldo
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Abstract
The present invention relates to methods and compositions which employ low concentrations of combinations of zinc salts to prevent the irritation of skin or mucous membranes that may be caused by therapeutic agents, by personal hygiene products, by articles such as gloves or condoms, or by various physical, chemical, mechanical, or biological irritants.
Claims67
A coating for application to an article, comprising:
- two water soluble zinc salts, each at a concentration of between 0.1 and 1 weight percent;
- a first water insoluble zinc salt at a concentration of between about 0.1 and 1 weight percent;
- panthenol at a concentration of between about 0.05 and 5 weight percent;
- and
- glycerin, at a concentration between about 0 and 5 weight percent.
A coating for application to an article, comprising:
- two water soluble zinc salts, each at a concentration of between 0.1 and 1 weight percent;
- panthenol at a concentration of between about 0.05 and 5 weight percent;
- and
- an effective amount of an antimicrobial agent.
A surgical hand wash, comprising:
- (i) two or more water soluble zinc salts wherein said zinc salts in total are present at a combined concentration of between about 0.1 and 0.5 percent (weight/weight);
- (ii) farnesol at a concentration of between about 0.3 and 1.0 percent (weight/weight);
- (iii) panthenol at a concentration of between about 0.2 and 5 percent (weight/weight);
- and
- (iv) a quaternary ammonium compound and a biguanide, wherein the total concentration of quaternary ammonium compound and biguainde is between about 0.05 and 2.0 percent (weight/weight).
A disinfectant soap, comprising:
- (i) two or more water soluble zinc salts, wherein said zinc salts in total are present at a combined concentration of between about 0.1 and 0.5 percent (weight/weight);
- (ii) farnesol at a concentration of between about 0.3 and 1.0 percent (weight/weight);
- (iii) panthenol at a concentration of between about 0.2 and 5 percent (weight/weight);
- and
- (iv) a quaternary ammonium compound and a second antimicrobial agent selected from the group consisting of a biguanide and a chlorinated phenol, wherein the total concentration of quaternary ammonium compound and second antimicrobial agent is between about 0.05 and 2.0 percent (weight/weight).
A composition comprising:
- at least one water soluble zinc salt at a concentration of between about 0.05 and 2.0% w/w;
- D,L panthenol at a concentration between about 0.05 and 5.0% w/w;
- and
- a gelling agent at a concentration of between about 0.05 and 0.3% w/w;
- where the composition provides an anti-irritant effect.
Dependencies are inferred from the claim text.