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US 7,745,187 B2Granted
Sulfotransferase sequence variants
AssigneeMayo Foundation for Medical Education and Research
InventorsRobert R Freimuth, Eric D Wieben, Richard M Weinshilboum
Life of this patent
Estimating the term…
Abstract
Isolated sulfotransferase nucleic acid molecules that include a nucleotide sequence variant and nucleotides flanking the sequence variant are described, as well as sulfotransferase allozymes. Methods for determining if a mammal is predisposed to thyroid disease or cancer also are described.
Claims7
An isolated SULT1C1 polypeptide variant comprising the sequence set forth in SEQ ID NO:
- 2 wherein amino acid residue 60, 73, 111 or 255 of SEQ ID NO:
- 2 is substituted with a different amino acid.
Dependencies are inferred from the claim text.