Drug-containing patch
AssigneeHisamitsu Pharmaceutical Co., Inc.
InventorsToshiro Yamaguchi, Mitsuru Kuribayashi
Life of this patent
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Abstract
The problem of the invention is to provide a drug-containing patch which is very favorable in percutaneous absorbability and is excellent in sustainability of the drug efficacy, that is, the drug-containing patch having a sufficient percutaneous absorbability and effect sustainability in a degree to be actually used for therapy of patients. The problem is solved by a patch comprising a drug, a melting point lowering agent and an adhesive base.
Claims9
A patch containing a drug selected from the group consisting of oxybutynin, fentanyl, pergolide, tandospirone, donepezil, tamsulosin, risperidone, flurazepam, butorphanol, perisoxal, pridinol, trihexyphenidyl, amantadine, tulobuterol, isoprenaline, propranolol, ketotifen, difenidol, morphine, meloxicam, valdecoxib and celecoxib, an adhesive base, at least one melting point lowering agent that lowers the melting point of the drug to increase skin permeation rate of the drug, wherein the melting point lowering agent is one or more selected from the group consisting of acetic acid, propionic acid, butyric acid, lactic acid, benzoic acid and salicylic acid, and a corresponding salt of the melting point lowering agent.
Dependencies are inferred from the claim text.