Biomaterials formed by nucleophilic addition reaction to conjugated unsaturated groups

A method for making a biomaterial, said method comprising combining two or more precursor components of said biomaterial under conditions that allow polymerization of the components, wherein said polymerization occurs through self selective reaction between a strong nucleophile and a conjugated unsaturated bond or a conjugated unsaturated group, by nucleophilic addition, wherein each of said precursor components comprises at least two strong nucleophiles or at least two conjugated unsaturated bonds or conjugated unsaturated groups, wherein one of said components comprises at least three strong nucleophiles or at least three conjugated unsaturated bonds or at least three conjugated unsaturated groups, and wherein said biomaterial does not comprise albumin in its natural state, and said unsaturated bonds or groups are not maleimide or a vinyl sulfone, thereby making said biomaterial.