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US 7,744,863 B1Granted
Method of inducing immune tolerance
OwnerBruce Milne Hall, Suzanne Jean Hodgkinsoninventors
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Abstract
A method of inhibiting Th1 immune response in a subject in need of such treatment which comprises administering to the subject effective amounts for inhibiting Th1 immune response of an anti-CD3 monoclonal antibody and IL-5 or an analogue or mimetic thereof.
Claims5
A method of inhibiting Th1 immune response in a mammalian subject suffering from an autoimmune disease, which method comprises administering to the mammalian subject effective amounts of an anti-CD3 monoclonal antibody and IL-5, or an anti-CD3 monoclonal antibody and an analogue of IL-5, wherein the autoimmune disease is selected from the group consisting of:
- type I diabetes, multiple sclerosis, rheumatoid arthritis, psoriasis, glomerulonephritis, myasthenia gravis, chronic inflammatory demyelinating neuropathy and inflammatory bowel disease.
Dependencies are inferred from the claim text.