Method and system for particle data processing
AssigneeBeckman Coulter, Inc.
InventorFrancisco Estevez-Labori
Life of this patent
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Abstract
In an embodiment, a computer-implemented method is provided for processing digital data from a particle analyzer. The method includes receiving digital particle data, transforming the received data to correct for noise, applying linear compensation for dye spectral overlap, and re-establishing the original dimensions of the data. Processed particle data may be used for display, analysis or storage. In another embodiment, a system comprises at least one particle analyzer coupled to a particle data corrector. The particle data corrector includes a transformer, a compensator, and a converter.
Claims14
A computer-implemented method for processing digital data from a particle analyzer, comprising:
- receiving raw particle data from the particle analyzer at a computer, wherein the raw particle data has noise including photon counting statistics error;
- transforming the raw particle data to obtain transformed particle data having reduced photon counting statistics error;
- compensating the transformed particle data for dye spectral overlap, to obtain compensated particle data;
- converting the compensated particle data to obtain converted particle data, having dimensions conforming to the raw particle data;
- and
- outputting the converted particle data.
A system for processing particle data from at least one light detector, comprising:
- at least one particle analyzer;
- a particle data corrector that receives from the at least one particle analyzer raw particle data having noise including photon counting statistics error;
- a display device, wherein the display device is coupled with the particle data corrector;
- and
- wherein the particle data corrector includes:
- a transformer that transforms the raw particle data to generate transformed particle data having reduced photon counting statistics error;
- a compensator that compensates the transformed particle data to generate compensated particle data having reduced dye spectral overlap;
- and
- a converter that converts the compensated particle data to generate converted particle data having dimensions conforming to said raw particle data.
A system for reducing noise in raw particle data generated from at least one light detector, the noise including photon counting statistics error, said system comprising:
- a transformer that transforms the raw particle data to generate transformed particle data having reduced photon counting statistics error;
- a compensator that compensates the transformed particle data to generate compensated particle data having reduced dye spectral spillover effects;
- a converter that processes the compensated particle data to generate converted particle data having dimensions conforming to said raw particle data;
- and
- an output interface that outputs the converted particle data.
A computer program product comprising a computer usable medium having control logic stored therein for causing a computer to process raw particle data from at least one light detector, the raw particle data having noise including photon counting statistics error, said control logic comprising:
- first computer readable program code that enables the computer to transform the raw particle data to generate transformed particle data having reduced photon counting statistics error;
- second computer readable program code that enables the computer to compensate the dye spectral overlap of the corrected particle data to generate compensated particle data;
- third computer readable program code that enables the computer to convert the compensated particle data to generate converted particle data having dimensions of the raw particle data;
- and
- fourth computer readable program code to enable the computer to output the converted particle data.
Dependencies are inferred from the claim text.