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AssigneesNovartis Vaccines and Diagnostics, Inc., J. Craig Venter Institute, Inc.
InventorsClaire Marie Fraser, Erin Kathleen Hickey, Jeremy D. Peterson, Herve Tettelin, Craig Ventor, Vega Masignani, Cesira Galeotti, Marirosa Mora, Giulio Ratti, Maria Scarselli, Vincenzo Scarlato, Rino Rappuoli, Mariagrazia Pizza, Guido Grandi
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The invention provides methods of obtaining immunogenic proteins from genomic sequences including Neisseria, including the amino acid sequences and the corresponding nucleotide sequences, as well as the genomic sequence of Neisseria meningitidis B. The proteins so obtained are useful antigens for vaccines, immunogenic compositions, and/or diagnostics.
An isolated and purified polynucleotide comprising the nucleotide of SEQ ID NO 35.
An isolated and purified polynucleotide comprising a nucleotide sequence having greater than 70% sequence identity to SEQ ID NO 35.
An isolated and purified polynucleotide which encodes a protein, wherein the polynucleotide comprises the nucleotide sequence of SEQ ID NO 35 or a complement thereof.
An isolated and purified polynucleotide which encodes a protein, wherein the polynucleotide comprises a nucleotide sequence having greater than 70% sequence identity to SEQ ID NO 35 or a complement thereof.
Dependencies are inferred from the claim text.