US 7,612,110 B2 · Utilization of dialkylfumarates

Abstract

The present invention relates to the use of certain dialkyl fumarates for the preparation of pharmaceutical preparations for use in transplantation medicine or for the therapy of autoimmune diseases and said compositions in the form of micro-tablets or pellets. For this purpose, the dialkyl fumarates may also be used in combination with conventional preparations used in transplantation medicine and immunosuppressive agents, especially cyclosporines.

Claims29

Dependent claims

A method of treating autoimmune polyarthritis but not treating psoriatic arthritis, comprising administering, to a patient in need of treatment for said polyarthritis but not for said psoriatic arthritis, an amount of a pharmaceutical preparation effective for treating said polyarthritis, the pharmaceutical preparation comprising

at least one excipient or at least one carrier or a combination thereof and
an active ingredient only consisting of dimethyl fumarate, methyl hydrogen fumarate, or a combination thereof.

Dependencies are inferred from the claim text.

Facts

Application

11/765,563Filed 20 Jun 2007 · division

Priority

DE 198 53 48719 Nov 1998

Published

US 2007/0248662 A125 Oct 2007

Granted

3 Nov 2009

Term ends

Not estimatedThe source records don’t support an estimate.

Classification36 codes

A61K 9/4891
Preparations in capsules, e.g. of gelatin, of chocolate: coated capsules; Multilayered drug free capsule shells
A61K 9/1676
With an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface: having a drug-free core…
A61K 9/2018
Organic compounds, e.g. phospholipids, fats: sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
A61K 9/2027
Organic macromolecular compounds: obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, polyacrylates

Family

PCT/EP99/08215Parent of this division · filed 29 Oct 1999

Application10/197,077Parent of this division · filed 17 Jul 2002

US 2007/0248662 A1Pre-grant publication · published 25 Oct 2007

US 7,320,999 B2Parent of this division

Application09/831,620Parent of this division

US 6,509,376 B1Parent of this division

US 2003/0018072 A1Published application

US 7,612,110 B2This patent

From the US filing history. Foreign family members aren’t listed.

Abstract

Facts

Application

11/765,563Filed 20 Jun 2007 · division

Priority

DE 198 53 48719 Nov 1998

Published

US 2007/0248662 A125 Oct 2007

Granted

3 Nov 2009

Term ends

Not estimatedThe source records don’t support an estimate.

Classification36 codes

A61K 9/4891
Preparations in capsules, e.g. of gelatin, of chocolate: coated capsules; Multilayered drug free capsule shells
A61K 9/1676
With an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface: having a drug-free core…
A61K 9/2018
Organic compounds, e.g. phospholipids, fats: sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
A61K 9/2027
Organic macromolecular compounds: obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, polyacrylates

Family

PCT/EP99/08215Parent of this division · filed 29 Oct 1999

Application10/197,077Parent of this division · filed 17 Jul 2002

US 2007/0248662 A1Pre-grant publication · published 25 Oct 2007

US 7,320,999 B2Parent of this division

Application09/831,620Parent of this division

US 6,509,376 B1Parent of this division

US 2003/0018072 A1Published application

US 7,612,110 B2This patent

From the US filing history. Foreign family members aren’t listed.

Utilization of dialkylfumarates

Life of this patent

Abstract

Claims29

Utilization of dialkylfumarates

Life of this patent

Abstract

Claims29