Sulfopyrroles

A compound of formula (I)

• wherein
• R1 represents C5-10 aryl, C5-10 aryl-C1-4 alkyl, C5-10 aryl-C2-4 alkenyl or 5 or 6-membered heteroaryl containing 1, 2, 3, or 4 heteroatoms selected from at least one of nitrogen, sulfur, and oxygen, wherein the aryl and the heteroaryl may be substituted by one to five substituents independently selected from C1-4 alkyl, halo-C1-4 alkyl, C1-4 alkoxy, di C1-7 alkylamino, halogen, and nitro;
• and wherein two adjacent substituents together with atoms of the aryl or the heteroaryl may form a 5 membered heterocyclic ring containing at least one oxygen atom;
• R2 is C5-10 aryl or 5 or 6-membered heteroaryl containing 1, 2, 3, or 4 heteroatoms selected from at least one of nitrogen, sulfur, and oxygen, wherein the aryl or the heteroaryl may be substituted by one to five substituents independently selected from
• C1-4 alkyl, C1-4 alkoxy, and halogen;
• and wherein two adjacent substituents together with atoms of the aryl or the heteroaryl may form a 5 membered heterocyclic ring containing two oxygen atoms;
• R3 represents a group CH2NR6R7;
• R6 represents hydrogen, C1-7 alkyl, phenyl-C1-4 alkyl optionally substituted by C1-4 alkoxy, or amino-C1-7 alkyl, wherein a nitrogen of the amino-C1-7 alkyl can be substituted by up to two substituents selected from C1-4 alkyl;
• C5-10 aryl substituted by one substituent selected from 5 or 6-membered heteroaryl containing 1, 2, 3 or 4 heteroatoms selected from at least one of nitrogen, sulfur, and oxygen, heterocyclyl containing 4-10 atoms compromising 1, 2, or 3 heteroatoms selected from at least one of nitrogen, sulfur, and oxygen, and a sulfamoyl group SO2NR4R5, wherein said substituent on the aryl may be directly linked or linked via a spacer selected from C1-4 alkylidene;
• and optionally one or two further substituents selected from C1-4 alkyl;
• C5-10 aryl substituted by cyano;
• or
• 5 or 6-membered heteroaryl containing 1, 2, 3 or 4 heteroatoms selected from at least one of nitrogen, sulfur, and oxygen;
• R4 represents hydrogen;
• R5 represents hydrogen;
• and
• R7 represents hydrogen, C1-4 alkyl, or C1-4 alkylcarbonyl;
• or salts thereof.