Back to results
US 7,611,867 B2Granted
CC-chemokine binding tick proteins
AssigneeMerck Serono SA
InventorsAmanda Proudfoot, Christine Power, Maud Deruaz
Life of this patent
Estimating the term…
Abstract
A novel CC-chemokine binding protein is isolated from the saliva of Rhipicephalus sanguineus. Compounds prepared in accordance with the present invention can be used as anti-inflammatory and immunomodulatory compounds and in the treatment or prevention of CC-chemokine-related diseases.
Claims31
An isolated polypeptide that:
- a) comprises SEQ ID NO:
- 5;
- b) comprises SEQ ID NO:
- 6;
- or
- c) a fusion protein comprising any one of a) or b) operably linked to a heterologous sequence selected from an extracellular domain of a membrane-bound protein, an immunoglobulin constant region, a multimerization domain, a heterodimeric protein hormone, a signal peptide, an export signal, or a tag sequence.
3 more elements
Dependencies are inferred from the claim text.