Surface enhanced raman spectroscopy with periodically deformed SERS-active structure
AssigneeHewlett-Packard Development Company, L.P.
InventorsWei Wu, Zhiyong Li, Shih-Yuan Wang, Zhaoning Yu, R. Stanley Williams
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Abstract
An apparatus and related methods for facilitating surface-enhanced Raman spectroscopy (SERS) is described. A SERS-active structure near which a plurality of analyte molecules is disposed is periodically deformed at an actuation frequency. A synchronous measuring device synchronized with the actuation frequency receives Raman radiation scattered from the analyte molecules and generates therefrom at least one Raman signal measurement.
Claims20
An apparatus for facilitating surface-enhanced Raman spectroscopy (SERS), comprising:
- a SERS-active structure near which a plurality of analyte molecules is disposed;
- an actuation device in actuable communication with the SERS-active structure, the actuation device periodically deforming the SERS-active structure at an actuation frequency;
- and
- a synchronous measuring device receiving Raman radiation scattered from the analyte molecules and generating therefrom at least one Raman signal measurement, wherein said synchronous measuring device is synchronized with said actuation frequency.
A method for facilitating surface-enhanced Raman spectroscopy (SERS), comprising:
- receiving a plurality of analyte molecules for attachment near a SERS-active structure;
- periodically deforming the SERS-active structure at an actuation frequency in a vicinity of the analyte molecules;
- and
- receiving Raman radiation scattered from the analyte molecules at a synchronous measuring device that generates at least one Raman signal measurement therefrom, the synchronous measuring device being synchronized with said actuation frequency.
An apparatus, comprising:
- a SERS-active structure near which a plurality of analyte molecules is disposed;
- means for detecting Raman radiation scattered from said analyte molecules;
- means for periodically deforming the SERS-active structure at an actuation frequency to cause an output of said means for detecting to be periodic at said actuation frequency;
- and
- means for synchronous processing of said output of said means for detecting to generate therefrom a Raman signal measurement, said means for synchronous processing using a reference frequency equal to said actuation frequency.
Dependencies are inferred from the claim text.