Hydrolytically degradable polymers and hydrogels made therefrom
AssigneeNektar Therapeutics
InventorsJ. Milton Harris, Michael D. Bentley, Xuan Zhao, Xiaoming Shen
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Abstract
A water soluble polymer is described, the water soluble polymer comprising multiple hydrolytically degradable carbonate linkages in a backbone and, for each carbonate linkage in the backbone, an oligomer linked thereto by the carbonate linkage, wherein the oligomer is branched and, prior to being linked by the carbonate linkage, has the formula: R3[O—(—CHR1CH2—O—)n—]mH where R3 is a core branching moiety, R1 is H, (n) can range from 2 to 2000, and m is at least 3.
Claims3
A water soluble polymer comprising multiple hydrolytically degradable carbonate linkages in a backbone and, for each carbonate linkage in the backbone, an oligomer linked thereto by the carbonate linkage, wherein the oligomer is branched and, prior to being linked by the carbonate linkage, has the formula:
- R3[O—(—CHR1CH2—O—)n—]mH
- where R3 is a core branching moiety, R1 is H, (n) can range from 2 to 2000, and m is at least 3.
Dependencies are inferred from the claim text.