6-azaindole compound

A compound represented by the formula

• wherein
• R1, R2, R3 and R6 are the same or different and each is a hydrogen atom, a halogen atom, an amino group, or a mono- or di-C7-19 aralkylamino group;
• R4 is a hydrogen atom;
• and
• R5 is
• 1) a group represented by the formula:
• —C(═X)—R7
• wherein X is N—O—R8 or N—NH—R9
• wherein R8 and R9 are the same or different and each is
• (i) a hydrogen atom;
• (ii) an amidino group;
• (iii) a C1-6 alkyl group optionally having 1 to 3 substituents selected from a hydroxy group, an optionally halogenated C1-6 alkoxy group, a carboxyl group, an amino group, a mono-or di-C1-6 alkylamino group, a 5- to 7-membered heterocyclic group, a C1-6 alkoxy-carbonyl group, a carbamoyl group, a mono- or di-C1-6 alkyl-carbamoyl group, a C6-14 aryl-carbamoyl group, a C1-6 alkoxy-carboxamido group and a 5- to 7-membered heterocyclic oxy group;
• (iv) a C7-19 aralkyl group;
• (v) a heterocyclic group bonded via a carbon atom and optionally having 1 to 3 C1-6 alkoxy-carbonyl groups;
• or
• (vi) a carbamoyl group, and
• R7is
• (i) a hydrogen atom or
• (ii) a C1-6 alkyl group, a C6-14 aryl group, a C7-19 aralkyl group or a monocyclic aromatic heterocyclic group, each of which may have 1 to 3 substituents selected from a halogen atom, a C1-6 alkyl group and an optionally halogenated C1-6 alkoxy group;
• 2) a group represented by the formula:
• —C(═O)—R10
• wherein R10
• (i) a hydrogen atom;
• (ii) a C1-6 alkyl group;
• (iii) C6-14 aryl group optionally having 1 to 3 substituents selected from a halogen atom, a C1-6 alkyl group and an optionally halogenated C1-6 alkoxy group;
• (iv) a C7-19 aralkyl group;
• or
• (v) a heterocyclic group bonded via a carbon atom;
• 3) a group represented by the formula:
• —CH(OH)—R10 wherein R10 is as defined above;
• 4) a group represented by the formula:
• —C(═O)—NH—(CH2)n-Ar wherein n is 0, 1 or 2, and Ar is a C6-14 aryl group or a 5 or 6-membered aromatic heterocyclic group;
• 5) a group represented by the formula:
• —C(═O)-Het wherein Het is 1-pyrrolidinyl, 1-piperazinyl, 4-morpholinyl or 4-thiomorpholinyl each optionally having 1 to 3 substituents selected from an optionally halogenated C1-6 alkyl group and an optionally halogenated C1-6 alkyl-carbonyl group;
• or
• 6) a group represented by the formula:
• —CH(R12)—NR13R14 wherein R12 is a hydrogen atom, C1-6 alkyl group or a C6-14 aryl group;
• R13 and R14 are the same or different and each is
• (i) a hydrogen atom,
• (ii) a C1-6 alkyl group, a C3-8cycloalkyl group or a C7-19 aralkyl group each optionally having one to three 5- to 7-membered heterocyclic groups,
• (iii) a monocyclic non-aromatic heterocyclic group optionally having 1 to 3 C7-19 aralkyl groups, or
• (iv) a C1-6 alkyl-carbonyl group, a C6-14 aryl-carbonyl group or an aromatic heterocyclic carbonyl group each optionally having 1 to 3 C1-6 alkoxy-carboxamido groups, or R13 and R14 form, together with the adjacent nitrogen atom, a nitrogen-containing heterocyclic group optionally having 1 to 3 substituents selected from a halogen atom, an optionally halogenated C1-6 alkyl group and an optionally halogenated C1-6 alkoxy group (provided that the nitrogen-containing heterocyclic group is not an oxopyrrolidinyl group or an oxopiperazinyl group),
• or a salt thereof.