Exendin 4 polypeptide fragment
AssigneeChangzhou Pharmaceutical Factory
InventorsXiaopeng Ma, Bing Wang, Shaoqi Xi
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Abstract
The present invention relates to an Exendin 4 polypeptide fragment, which has hypoglycemic activity, and can be used for the treatment of type II diabetes mellitus. The polypeptide sequence described herein is HGEGTX1TSDLSKQX2EEEAVX3LFIEWLKNGX4PX5, where X1 represents Phe or Tyr, X2 represents Met, Ile or Leu, X3 represents Lys, X4 represents Gly or deletion, X5 represents Arg or deletion. Additionally, the present invention relates to a method for the Exendin 4 polypeptide fragment preparation.
Claims10
A polypeptide, pharmaceutically acceptable salt, or ester thereof, comprising the sequence represented by SEQ ID 73.
Dependencies are inferred from the claim text.