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US 7,608,581 B2Granted
Biofunctional, antimicrobial coatings for medical devices
AssigneeAffinergy, Inc.
InventorsPaul Hamilton, Daniel Kenan, Mark Grinstaff
Life of this patent
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AssigneeAffinergy, Inc.
InventorsPaul Hamilton, Daniel Kenan, Mark Grinstaff
Estimating the term…
The present invention provides compositions and methods for an improved coating for medical devices. Provided is an interfacial biomaterial or biofunctional coating composition comprising at least one binding domain that has bind specificity for a surface material of a medical device, and at least one binding domain that has binding specificity for an antimicrobial composition. Methods for coating a surface of a medical device, and for manufacturing of a medical device, comprise contacting the surface to be coated with the biofunctional coating material in an amount effective to form a coating.
A medical device comprising at least one surface coated with a coating for imparting antimicrobial activity to the medical device, wherein the coating comprises a surface-binding domain coupled to an antimicrobial-binding domain, wherein the surface-binding domain comprises a peptide that binds non-covalently to a material of which the medical device is comprised, and wherein the antimicrobial-binding domain comprises a peptide that binds non-covalently to an antibiotic composition.
Dependencies are inferred from the claim text.