Method for cancer detection, progression analysis and malign tumour prognosis based on the study of metabolic markers of the cell

A method for cancer detection, cancer progression analysis and malign tumor progression in cancer cells, comprising the steps of:

• detecting the expression level of the polypeptide of subunit β of H(+)-ATP synthase of the cancer cells;
• calculating a ration of the expression of β-F1-ATPase to Hsp60 of the cancer cells;
• and
• comparing the ration with a ratio of β-F1-ATPase to Hsp60 of one of a) control non-cancerous cells of a same cellular type as the cancer cells and b) control cancer cells of a same cellular type as the cancer cells,
• wherein, if the ratio of the cancer cells is lower than the ratio of the control non-cancerous cells, a presence of cancer is indicated, and
• wherein, if the ratio of the cancer cells is lower than the ratio of the control cancer cells, that the cancer cells are further progressed cancer cells is implied and a subject from which the cancer cells were obtained has a worse prognosis than a subject from which the control cancer cells were obtained is implied.