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US 7,608,282 B2Granted
Transdermal granisetron
AssigneeStrakan International Limited
InventorsPeter Altenschöpfer, Adam Charles Watkinson
Life of this patent
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Abstract
Adhesive patches for the transdermal administration of granisetron, comprise an acrylic adhesive containing non-acidic nucleophilic moieties which substantially increase flux of granisetron across the skin.
Claims28
An adhesive patch suitable for the transdermal administration of granisetron to a subject in need thereof, said patch comprising:
- an acrylic adhesive consisting essentially of:
- 50 to 98% w/w of a primary acrylate monomer wherein said primary acrylate monomer is either 2-ethylhexyl acrylate or butyl acrylate, and
- 0.5 to 20% w/w of a monomer containing non-acidic hydroxyl moieties, and
- a physiologically effective amount of granisetron loaded in the acrylic adhesive,
- wherein the granisetron content of said patch remains substantially unchanged when stored at 25° C. for six weeks.
2 more elements
Dependencies are inferred from the claim text.