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US 7,608,265 B2Granted
Treatment for bacterial infections
AssigneeNeuTec Pharma PLC
InventorsJames Peter Burnie, Ruth Christine Matthews, Tracey Carter
Life of this patent
Estimating the term…
Abstract
The present invention is concerned with compounds, medicaments and treatments for Clostridium difficile infection, together with novel isolated antibodies and their use in same. The present invention is also concerned with the treatment and prophylaxis of E. faecium and E. faecalis infection and provides medicaments and treatments for same.
Claims4
An isolated antibody or antigen binding fragment thereof that binds acetyl-coA-acetyltransferase of Clostridium difficile, the antigen or antigen binding fragment thereof comprising:
- (i) a heavy chain, wherein complementarity determining region 1 comprises the amino acid sequence of SEQ ID NO:
- 2, complementarity determining region 2 comprises the amino acid sequence of SEQ ID NO:
- 3 and complementarity determining region 3 comprises the amino acid sequence of SEQ ID NO:
- 4, and
- (ii) a light chain, wherein complementarity determining region 1 comprises the amino acid sequence of SEQ ID NO:
- 17, complementarity determining region 2 comprises the amino acid sequence of SEQ ID NO:
- 18 and complementarity determining region 3 comprises the amino acid sequence of SEQ ID NO:
- 19.
5 more elements
Dependencies are inferred from the claim text.