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US 7,608,246 B2Granted
Apolipoprotein E as an adjuvant for lipid antigens
AssigneeThe Brigham and Women's Hospital, Inc.
InventorsPeter van den Elzen, Michael B. Brenner
Life of this patent
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Abstract
The present invention is directed to pharmaceutical compositions that contain a combination of apolipoprotein E and an antigenic lipid. The compositions may be administered to a subject for the purpose of inducing an immune response against the lipid and in immunization protocols.
Claims1
A method of inducing the production of antibodies against an antigenic lipid, comprising administering to a subject capable of antibody production a composition comprising:
- a) said antigenic lipid;
- and
- b) apolipoprotein E in an amount that, together with said antigenic lipid, is sufficient to induce production of said antibodies.
Dependencies are inferred from the claim text.