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AssigneeGe Healthcare Limited
InventorsAlan Cuthbertson, Marivi Mendizabal, Mark Dixon, Anthony E. Storey, Edward R. Bacon, Vinay Chandrakant Desai, Sudhakar Kasina, Henry Raphael Wolfe
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A peptide-chelate conjugate with affinity for the ST receptor is disclosed, wherein the chelate is tetradentate. The peptide-chelate conjugate of the invention may be labelled with a radiometal to provide a metal complex. A radiopharmaceutical composition comprising the metal complex is provided. which is suitable for the diagnostic imaging of colorectal cancer. Also provided for in the invention is a kit for the preparation of the radiopharmaceutical preparation.
A peptide-chelate conjugate comprising a peptide of SEQ ID Nos. 1 to 7 having affinity for the ST receptor conjugated to a tetradentate chelating agent, where the tetradentate chelating agent is chosen from diaminedioximes and N3S ligands.
Dependencies are inferred from the claim text.