Medical device for delivery of a biologically active material to a lumen

An apparatus for delivering a biologically active material to a body lumen comprising:

• (a) a catheter having a distal portion, a proximal portion and a first lumen therethrough;
• (b) a balloon disposed at the distal portion of the catheter, wherein the balloon has an interior compartment in fluid communication with the first lumen of the catheter;
• the balloon has an outer surface having a plurality of micro-needles disposed thereon;
• and each micro-needle of said plurality of micro-needles has a lumen in fluid communication with the interior compartment and wherein the micro-needles are capable of being ruptured;
• and
• (c) a triggering source to rupture the micro-needles when activated to deliver the biologically active material from the interior compartment of the balloon through the micro-needle lumens to the body lumen, wherein the triggering source is selected from the group consisting of a shockwave, ultrasound energy and energy source for delivering a detachable coil.