Method of 2D-NMR correlation spectroscopy with double quantum filtration followed by evolution of single quantum transitions
AssigneeBruker BioSpin GmbH
InventorsNarayanan Chandrakumar, Velusamy Ramesh
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Abstract
A method of 2-dimensional nuclear magnetic resonance (2D-NMR) correlation spectroscopy, comprises a pulse sequence with the following steps: excitation of double quantum coherence; immediate reconversion to single transition single quantum coherence; evolution of the set of single transitions; mixing with zero quantum mixing Hamiltonian; and signal detection. The method can achieve an improved sensitivity, has a transition selectivity and suppresses diagonal peaks.
Claims17
A method of 2-dimensional nuclear magnetic resonance (2D-NMR) correlation spectroscopy having a pulse sequence comprising the following steps:
- a) exciting a double quantum coherence;
- b) immediately reconverting to single transition, single quantum coherence;
- c) evolving a set of single transitions;
- d) mixing with a zero quantum mixing Hamiltonian;
- and
- e) detecting signals.
A method of 2D-NMR correlation spectroscopy having a pulse sequence comprising the following steps:
- a) exciting a double quantum coherence;
- b) immediately reconverting using a 90° pulse;
- c) evolving a set of anti-phase single quantum transitions;
- d) mixing with a zero quantum mixing Hamiltonian;
- and
- e) detecting signals.
Dependencies are inferred from the claim text.