Synthesizing method for compound, and catalyst for synthesis reaction
AssigneesCambridge University Technical Services Limited, Daihatsu Motor Co., Ltd.
InventorsSteven V. Ley, Martin D. Smith, Chandrashekar Ramarao, Antonia F. Stepan, Hirohisa Tanaka
Life of this patent
Estimating the term…
Abstract
A catalyst for synthesis reaction that can allow the cross coupling reaction at an improved yield, and yet can be collected after used for the reaction and recycled, and a synthesizing method for a compound using the same catalyst for synthesis reaction. In the Suzuki cross-couplings given by the following reaction formula (15), palladium containing perovskite-like composite oxide is used as a catalyst for synthesis reaction:
Claims5
A synthesizing method for a compound, wherein a compound indicated in a formula (1) given below, and a compound indicated in a formula (2) given below or a compound indicated in a formula (3) given below are allowed to react with each other in the presence of a perovskite-like composite oxide comprising palladium:
- R1—X (1)
- wherein in formula (1), R1 represents an aryl group that may have a substituent, a heterocyclic group that may have a substituent, or an alkenyl group that may have a substituent, and X represents a halogen atom, a triflouromethanesulfonyloxy group, a p-toluenesulfonyloxy group, or a methanesulfonyloxy group;
- and
- R2-M (2)
- wherein in formula (2), R2 represents an aryl group that may have a substituent, a heterocyclic group that may have a substituent, or an alkenyl group that may have a substituent, M represents a —B(ORa)2 group or a —Sn(Rb)3 group, Ra represents a hydrogen atom or an alkyl group that may have a substituent, and Rb represents an alkyl group;
- wherein as a substitute for Ra, an arylene group that may have a substituent or an alkylene group that may have a substituent may be used as a bonding hand of —OBO—, to form a ring including the —OBO—;
- and
- R3HC ═CR4R5 (3)
- wherein in formula (3), R3, R4, and R5 each represent a hydrogen atom, an alkyl group that may have a substituent, an aryl group that may have a substituent, a carboxylic acid derivative, an acid amide derivative, or a cyano group.
Dependencies are inferred from the claim text.