DCRS5 polypeptides
AssigneeSchering Corporation
InventorsMadaline Chirica, Robert A. Kastelein, Kevin W. Moore, Christi L. Parham
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Abstract
Nucleic acids encoding mammalian, e.g., primate, receptors, purified receptor proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are described.
Claims6
A substantially pure or recombinant polypeptide comprising a sequence having at least 95% sequence identity with SEQ ID NO:2, wherein the polypeptide, when combined along with IL-12Rβ1, is able to form a functional receptor complex for p40/IL-B30.
A substantially pure or recombinant polypeptide comprising a sequence having at least 98% sequence identity with SEQ ID NO:2, wherein the polypeptide, when combined along with IL-12Rβ1, is able to form a functional receptor complex for p40/IL-B30.
Dependencies are inferred from the claim text.