Inhibitors of NADH:ubiquinone oxidoreductase

A compound represented by the following structure:

• wherein:
• A is a π-bond that is either present or absent;
• R1 and R2 are radicals independently selected from the group consisting of —H, —F, —Cl, and —Br;
• R3 and R4 are —H;
• R5, R6 and R7 are radicals independently selected from the group consisting of —H, —OMe, —F, —Cl, and —Br;
• Z is —(CH2)—;
• X is carbon;
• Y is a diradical or pair of radicals selected from the group consisting of ═O, ═S, ═CH2, ═CF2, ═NOH, ═NOMe, and ═NOBn;
• and
• n is 0.