GBS toxin receptor antibodies
AssigneeVanderbilt University
InventorsCarl G. Hellerqvist, Changlin Fu
Life of this patent
Estimating the term…
Abstract
A novel GBS toxin receptor and methods for its preparation and use are provided. GBS toxin receptor polynucleotides and polypeptides and antibodies to GBS toxin receptor are provided, as well as detection, screening, and therapeutic methods and pharmaceutical compositions involving such polynucleotides, polypeptides and antibodies.
Claims10
An isolated antibody or a fragment thereof, wherein the antibody or the fragment thereof recognizes a mammalian GBS toxin receptor and wherein the GBS toxin receptor has at least about 86% identity to SEQ ID NO:8.
A composition for detection of a GBS toxin receptor comprising an isolated antibody or a fragment thereof that binds the GBS toxin receptor, wherein the GBS toxin receptor has at least about 86% identity to SEQ ID NO:
- 8.
A composition for detection of a GBS toxin receptor in a cell or a tissue, comprising an isolated antibody or a fragment thereof that binds the GBS toxin receptor, wherein the GBS toxin receptor has at least about 86% identity to SEQ ID NO:
- 8.
An isolated antibody or a fragment thereof, wherein the antibody or the fragment thereof binds a mammalian GBS toxin receptor and inhibits the binding of a GBS toxin to the mammalian GBS toxin receptor, wherein the GBS toxin receptor has at least about 86% identity to SEQ ID NO:
- 8.
An isolated composition comprising an antibody or a fragment thereof, wherein the antibody or the fragment thereof recognizes a mammalian GBS toxin receptor, and wherein the GBS toxin receptor has at least about 86% identity to SEQ ID NO:8.
Dependencies are inferred from the claim text.