Human voltage gated sodium channel β1A subunit and methods of use
AssigneeOrtho-McNeil Pharmaceutical, Inc.
InventorsNing Qin, Ellen Codd, Michael D'Andrea
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Abstract
DNAs encoding human voltage gated sodium channel β1A subunit have been cloned and characterized. The recombinant protein is capable of forming biologically active protein. The cDNA's have been expressed in recombinant host cells that produce active recombinant protein. The recombinant protein is also purified from the recombinant host cells. In addition, the recombinant host cells are utilized to establish a method for identifying modulators of the receptor activity, and receptor modulators are identified.
Claims2
An isolated protein encoded by a nucleic acid sequence having the sequence of SEQ ID NO:
- 12.
Dependencies are inferred from the claim text.