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US 7,407,645 B2Granted
Bioconjugates of metal complexes of nitrogen-containing macrocyclic ligands
AssigneeMetaPhore Pharmaceuticals, Inc.
InventorsWilliam L. Neumann, Dennis P. Riley, Randy H. Weiss, Susan L. Henke, Patrick J Lennon, Karl W. Aston
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Abstract
The present invention is directed to bioconjugates of complexes represented by the formula: wherein R, R′, R1, R′1, R2, R′2, R3, R′3, R4, R′4, R5, R′5, R6, R′6, R7, R′7, R8, R′8, R9, R′9, M, X, Y, Z and n are defined herein for use as contrast agents in diagnostic imaging.
Claims5
A compound which is complex represented by the
- wherein said biomolecule is independently selected from the group consisting of steroids, carbohydrates, fatty acids, amino acids, peptides, proteins, antibodies, vitamins, lipids, phospholipds, phosphates, phosphonates, nucleic acids, enzyme substrates, enzyme inhibitors and enzyme receptor substrates.
Dependencies are inferred from the claim text.